Description
Buprenorphine and naloxone 8mg/2mg
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl). It relieves cravings to use and withdrawal symptoms. Buprenorphine naloxone is available for use in two different forms, under the tongue or in the cheek.
Buprenorphine Buccal Film Prescribing Information
Prescribing Information (FDA)
Buprenorphine and naloxone sublingual film is indicated for treatment of opioid dependence. Buprenorphine and naloxone sublingual film should be used as part of a complete treatment plan that includes counseling and psychosocial support. Buprenorphine and naloxone sublingual film is administered sublingually.
Side effects may include respiratory depression (decreased breathing), small pupils, sleepiness, and low blood pressure.The risk of overdose with buprenorphine / naloxone (unless combined with other sedating substances) is exceedingly low, and lower than with methadone, but people are more likely to stop treatment on buprenorphine/naloxone than methadone. Buprenorphine (like methadone) is a treatment option during pregnancy.
